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Anyone writing about tobacco research stands on the shoulders of many giants. I offer grateful thanks to the world's hundreds of nicotine and tobacco scientists, particularly those who reviewed portions of the manuscript and offered suggestions: Neal Benowitz, Warren Bickel, Steve Heishman, Jack Henningfield, David Gilbert, Harry Lando, Ed Lichtenstein, Ken Perkins, and Gary Swan. James Picht's insights also were helpful.

I also offer my gratitude to the anonymous smoker whose story creates the framework for the book.

Additionally, I am thankful that Stephen Mautner of Joseph Henry Press was sufficiently enchanted with the prospectus for this book to encourage me to proceed.

And I can never offer enough warm words about my family and other loved ones for their continuing endurance and good humor.

Janet Brigham
Menlo Park, California
February 1998

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