%0 Book %A National Academies of Sciences, Engineering, and Medicine %A National Academy of Medicine %E Capron, Alexander %E GarcĂ­a, Patricia %E Schenk, Ellen %T Public Health Lessons for Non-Vaccine Influenza Interventions: Looking Past COVID-19 %@ 978-0-309-08817-6 %D 2022 %U https://nap.nationalacademies.org/catalog/26283/public-health-lessons-for-non-vaccine-influenza-interventions-looking-past %> https://nap.nationalacademies.org/catalog/26283/public-health-lessons-for-non-vaccine-influenza-interventions-looking-past %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 216 %X The COVID-19 pandemic has challenged the world's preparedness for a respiratory virus event. While the world has been combating COVID-19, seasonal and pandemic influenza remain imminent global health threats. Non-vaccine public health control measures can combat emerging and ongoing influenza outbreaks by mitigating viral spread. Public Health Lessons for Non-Vaccine Influenza Interventions examines provides conclusions and recommendations from an expert committee on how to leverage the knowledge gained from the COVID-19 pandemic to optimize the use of public health interventions other than vaccines to decrease the toll of future seasonal and potentially pandemic influenza. It considers the effectiveness of public health efforts such as use of masks and indoor spacing, use of treatments such as monoclonal antibodies, and public health communication campaigns. %0 Book %A National Academies of Sciences, Engineering, and Medicine %A National Academy of Medicine %E Anupindi, Ravi %E Yadav, Prashant %E Jefferson, Kenisha M.P. %E Ashby, Elizabeth %T Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines %@ 978-0-309-08915-9 %D 2022 %U https://nap.nationalacademies.org/catalog/26285/globally-resilient-supply-chains-for-seasonal-and-pandemic-influenza-vaccines %> https://nap.nationalacademies.org/catalog/26285/globally-resilient-supply-chains-for-seasonal-and-pandemic-influenza-vaccines %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 264 %X Influenza viruses, both seasonal and pandemic, have the potential to disrupt the health and well-being of populations around the world. The global response to the COVID-19 pandemic and prior public health emergencies of international concern illustrate the importance of global preparedness and coordination among governments, academia, scientists, policy makers, nongovernmental organizations, the private sector, and the public to address the threat of pandemic influenza. These health emergencies have revealed opportunities to enhance global vaccine infrastructure, manufacturing, distribution, and administration. Globally Resilient Supply Chains for Seasonal and Pandemic Influenza Vaccines outlines key findings and recommendations to bolster vaccine distribution, manufacturing, and supply chains for future seasonal and pandemic influenza events. This report addresses the challenges of manufacturing and distributing vaccines for both seasonal and pandemic influenza, highlighting the critical components of vaccine manufacturing and distribution and offering recommendations that would address gaps in the current global vaccine infrastructure. %0 Book %A National Academies of Sciences, Engineering, and Medicine %A National Academy of Medicine %E Sands, Peter %E Winters, Janelle %T Countering the Pandemic Threat Through Global Coordination on Vaccines: The Influenza Imperative %@ 978-0-309-08870-1 %D 2022 %U https://nap.nationalacademies.org/catalog/26284/countering-the-pandemic-threat-through-global-coordination-on-vaccines-the %> https://nap.nationalacademies.org/catalog/26284/countering-the-pandemic-threat-through-global-coordination-on-vaccines-the %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 236 %X The COVID-19 pandemic has laid bare the fragility of the global system of preparedness and response to pandemics and the fragmentation of our research and development ecosystem. The pandemic has provided a disruptive moment to advance new norms and frameworks for influenza. It also has demonstrated how innovative global public-private partnerships and coordination mechanisms can lead to rapid successes in viral vaccine research, manufacturing, and risk pooling. Countering the Pandemic Threat Through Global Coordination on Vaccines identifies ways to strengthen pandemic and seasonal influenza global coordination, partnerships, and financing. This report presents seven overarching recommendations for how the urgent influenza threat should be conceptualized and prioritized within the global pandemic preparedness and response agenda in the future. %0 Book %A National Academies of Sciences, Engineering, and Medicine %A National Academy of Medicine %E Bond, Enriqueta %E Subbarao, Kanta %E Soltani, Hoda %T Vaccine Research and Development to Advance Pandemic and Seasonal Influenza Preparedness and Response: Lessons from COVID-19 %@ 978-0-309-08781-0 %D 2022 %U https://nap.nationalacademies.org/catalog/26282/vaccine-research-and-development-to-advance-pandemic-and-seasonal-influenza-preparedness-and-response %> https://nap.nationalacademies.org/catalog/26282/vaccine-research-and-development-to-advance-pandemic-and-seasonal-influenza-preparedness-and-response %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 178 %X The global response to COVID-19 has demonstrated the importance of vigilance and preparedness for infectious diseases, particularly influenza. There is a need for more effective influenza vaccines and modern manufacturing technologies that are adaptable and scalable to meet demand during a pandemic. The rapid development of COVID-19 vaccines has demonstrated what is possible with extensive data sharing, researchers who have the necessary resources and novel technologies to conduct and apply their research, rolling review by regulators, and public-private partnerships. As demonstrated throughout the response to COVID-19, the process of research and development of novel vaccines can be significantly optimized when stakeholders are provided with the resources and technologies needed to support their response. Vaccine Research and Development to Advance Pandemic and Seasonal Influenza Preparedness and Response focuses on how to leverage the knowledge gained from the COVID-19 pandemic to optimize vaccine research and development (R&D) to support the prevention and control of seasonal and pandemic influenza. The committee's findings address four dimensions of vaccine R&D: (1) basic and translational science, (2) clinical science, (3) manufacturing science, and (4) regulatory science.