%0 Book %A National Research Council %T Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 4 %@ 978-0-309-09147-3 %D 2004 %U https://nap.nationalacademies.org/catalog/10902/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-4 %> https://nap.nationalacademies.org/catalog/10902/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-4 %I The National Academies Press %C Washington, DC %G English %K Environment and Environmental Studies %P 309 %X The Bhopal Disaster of 1984 resulted in the death of around 2,000 residents living near chemical plants and irreversible injuries to more than 20,000 other residents. These numbers can be attributed to the community's lack of awareness concerning the chemicals' existence, dangers and effects, and/or how to react in case of emergency. The disaster emphasized the need for governments to identify hazardous substances and to aid local communities in developing plans for emergency exposures. As a result, the United States government issued the Superfund Amendments and Reauthorization Act (SARA) of 1986; requiring the identification of extremely hazardous substances (EHSs) by the Environmental Protection Agency (EPA). EPA was also tasked with assisting Local Emergency Planning Committees (LEPCs) in conducting health-hazard assessments to develop emergency-response plans for sites where EHSs are produced, stored, transported, or used. The EPA identified nearly 400 EHSs in terms of their immediate danger to life and health (IDLH) as their first step in assisting these LEPCs. In 1991 the EPA went on to request that the National Research Council (NRC) Committee on Toxicology (COT) develop criteria and methods for developing emergency exposure levels for EHSs for the general population. The COT, who had published many reports on emergency exposure guidance levels at the time, designated the task to a subcommittee. The subcommittee focused on Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances. Four years later the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances (NAC) was created with a focus on identifying, reviewing, and interpreting relevant toxicologic and other scientific data and developing acute exposure guideline levels (AEGLs) for high-priority, acutely toxic chemicals. In Acute Exposure Guideline Levels for Selected Airborne Chemicals:Volume 4, the NAC outlines acute exposure guideline levels for chlorine, hydrogen chloride, toluene 2,4, hydrogen fluoride, 2,6-diisocyanate, and uranium hexafluoride. %0 Book %A National Research Council %T Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 7 %@ 978-0-309-12755-4 %D 2009 %U https://nap.nationalacademies.org/catalog/12503/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-7 %> https://nap.nationalacademies.org/catalog/12503/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-7 %I The National Academies Press %C Washington, DC %G English %K Environment and Environmental Studies %P 250 %X This book is the seventh volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and includes AEGLs for acetone cyanohydrin, carbon disulfide, monochloroacetic acid, and phenol. At the request of the Department of Defense, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for 12 new chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies such as accidental or intentional chemical releases in the community, the workplace, transportation, the military, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts. %0 Book %A National Research Council %T Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 5 %@ 978-0-309-10358-9 %D 2007 %U https://nap.nationalacademies.org/catalog/11774/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-5 %> https://nap.nationalacademies.org/catalog/11774/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-5 %I The National Academies Press %C Washington, DC %G English %K Environment and Environmental Studies %P 292 %0 Book %A National Research Council %T Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 6 %@ 978-0-309-11213-0 %D 2008 %U https://nap.nationalacademies.org/catalog/12018/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-6 %> https://nap.nationalacademies.org/catalog/12018/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-6 %I The National Academies Press %C Washington, DC %G English %K Environment and Environmental Studies %K Health and Medicine %P 320 %X This book is the sixth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and includes AEGLs for chemicals such as ammonia, nickel carbonyl and phosphine, among others. At the request of the Department of Defense, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for 12 new chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies such as accidental or intentional chemical releases in the community, the workplace, transportation, the military, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts. %0 Book %A National Research Council %T Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 3 %@ 978-0-309-08883-1 %D 2003 %U https://nap.nationalacademies.org/catalog/10672/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-3 %> https://nap.nationalacademies.org/catalog/10672/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-3 %I The National Academies Press %C Washington, DC %G English %K Environment and Environmental Studies %P 515 %X This report reviews documents on acute exposure guideline levels (AEGLs) for nerve agents GA (tabun), GB (sarin), GD (soman), GD, and VX, sulfur mustard, diborane, and methyl isocyanate. The documents were developed by the National Advisory Committee on Acute Exposure Guideline Levels for Hazardous Chemicals (NAC). The subcommittee concludes that the AEGLs developed in those documents are scientifically valid conclusions based on data reviewed by NAC and are consistent with the NRC reports on developing acute exposure guideline levels. %0 Book %A National Research Council %T Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 8 %@ 978-0-309-14515-2 %D 2010 %U https://nap.nationalacademies.org/catalog/12770/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-8 %> https://nap.nationalacademies.org/catalog/12770/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-8 %I The National Academies Press %C Washington, DC %G English %K Environment and Environmental Studies %K Health and Medicine %P 464 %X This book is the eighth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and reviews AEGLs for acrolein, carbon monoxide, 1,2-dichloroethene, ethylenimine, fluorine, hydrazine, peracetic acid, propylenimine, and sulfur dioxide for scientific accuracy, completeness, and consistency with the NRC guideline reports. %0 Book %A National Research Council %T Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 10 %@ 978-0-309-21987-7 %D 2011 %U https://nap.nationalacademies.org/catalog/13247/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-10 %> https://nap.nationalacademies.org/catalog/13247/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-10 %I The National Academies Press %C Washington, DC %G English %K Environment and Environmental Studies %P 322 %X Extremely hazardous substances (EHSs)&sup2 can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. As part of its efforts to develop acute exposure guideline levels for EHSs, EPA and the Agency for Toxic Substances and Disease Registry (ATSDR) in 1991 requested that the National Research Council (NRC) develop guidelines for establishing such levels. In response to that request, the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993. Subsequently, Standard Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances was published in 2001, providing updated procedures, methodologies, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels for Hazardous Substances and the Committee on Acute Exposure Guideline Levels (AEGLs) in developing the AEGL values. In 1998, EPA and DOD requested that the NRC independently review the AEGLs developed by NAC. In response to that request, the NRC organized within its Committee on Toxicology (COT) the Committee on Acute Exposure Guideline Levels, which prepared this report. Acute Exposure Guideline Levels for Selected Airborne Chemicals is the tenth volume of the series and documents for N,N-dimethylformamide, jet propellant fuels 5 and 8, methyl ethyl ketone, perchloromethyl mercaptan, phosphorus oxychloride, phosphorus trichloride, and sulfuryl chloride. %0 Book %A National Research Council %T Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 15 %@ 978-0-309-29122-4 %D 2013 %U https://nap.nationalacademies.org/catalog/18449/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-15 %> https://nap.nationalacademies.org/catalog/18449/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-15 %I The National Academies Press %C Washington, DC %G English %K Environment and Environmental Studies %P 294 %X Acute Exposure Guideline Levels for Selected Airborne Chemicals, Volume 15 identifies, reviews, and interprets relevant toxicologic and other scientific data for ethyl mercaptan, methyl mercaptan, phenyl mercaptan, tert-octyl mercaptan, lewisite, methyl isothiocyanate, and selected monoisocyanates in order to develop acute exposure guideline levels (AEGLs) for these high-priority, acutely toxic chemicals. AEGLs represent threshold exposure limits (exposure levels below which adverse health effects are not likely to occur) for the general public and are applicable to emergency exposures ranging from 10 minutes (min) to 8 h. Three level—AEGL-1, AEGL-2, and AEGL-3—are developed for each of five exposure periods (10 min, 30 min, 1 h, 4 h, and 8 h) and are distinguished by varying degrees of severity of toxic effects. This report will inform planning, response, and prevention in the community, the workplace, transportation, the military, and the remediation of Superfund sites.