%0 Book %T (NAS Colloquium) The Neurobiology of Pain %D 1999 %U https://nap.nationalacademies.org/catalog/9630/nas-colloquium-the-neurobiology-of-pain %> https://nap.nationalacademies.org/catalog/9630/nas-colloquium-the-neurobiology-of-pain %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %K Health and Medicine %P 144 %0 Book %T (NAS Colloquium) Geology, Mineralogy, and Human Welfare %D 1999 %U https://nap.nationalacademies.org/catalog/9470/nas-colloquium-geology-mineralogy-and-human-welfare %> https://nap.nationalacademies.org/catalog/9470/nas-colloquium-geology-mineralogy-and-human-welfare %I The National Academies Press %C Washington, DC %G English %K Earth Sciences %K Environment and Environmental Studies %P 144 %0 Book %T (NAS Colloquium) Plants and Population: Is There Time? %D 1999 %U https://nap.nationalacademies.org/catalog/9619/nas-colloquium-plants-and-population-is-there-time %> https://nap.nationalacademies.org/catalog/9619/nas-colloquium-plants-and-population-is-there-time %I The National Academies Press %C Washington, DC %G English %K Agriculture %K Environment and Environmental Studies %P 112 %0 Book %T (NAS Colloquium) Genetic Engineering of Viruses and Viral Vectors %D 1996 %U https://nap.nationalacademies.org/catalog/5708/nas-colloquium-genetic-engineering-of-viruses-and-viral-vectors %> https://nap.nationalacademies.org/catalog/5708/nas-colloquium-genetic-engineering-of-viruses-and-viral-vectors %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %K Environment and Environmental Studies %P 144 %0 Book %E Lindquist, Susan %E Henikoff, Steve %T Self-Perpetuating Structural States in Biology, Disease, and Genetics %D 2002 %U https://nap.nationalacademies.org/catalog/10620/self-perpetuating-structural-states-in-biology-disease-and-genetics %> https://nap.nationalacademies.org/catalog/10620/self-perpetuating-structural-states-in-biology-disease-and-genetics %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %K Health and Medicine %P 140 %0 Book %T (NAS Colloquium) Virulence and Defense in Host--Pathogen Interactions: Common Features Between Plants and Animals %D 2001 %U https://nap.nationalacademies.org/catalog/10099/nas-colloquium-virulence-and-defense-in-host-pathogen-interactions-common %> https://nap.nationalacademies.org/catalog/10099/nas-colloquium-virulence-and-defense-in-host-pathogen-interactions-common %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %P 124 %0 Book %T (NAS Colloquium) Genetics and the Origin of Species: From Darwin to Molecular Biology 60 Years After Dobzhansky %D 1997 %U https://nap.nationalacademies.org/catalog/5923/nas-colloquium-genetics-and-the-origin-of-species-from-darwin %> https://nap.nationalacademies.org/catalog/5923/nas-colloquium-genetics-and-the-origin-of-species-from-darwin %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %P 121 %0 Book %A National Academy of Sciences %T Biographical Memoirs: Volume 63 %@ 978-0-309-04976-4 %D 1994 %U https://nap.nationalacademies.org/catalog/4560/biographical-memoirs-volume-63 %> https://nap.nationalacademies.org/catalog/4560/biographical-memoirs-volume-63 %I The National Academies Press %C Washington, DC %G English %K Biography and Autobiography %P 546 %X Biographic Memoirs: Volume 63 contains the biographies of deceased members of the National Academy of Sciences and bibliographies of their published works. Each biographical essay was written by a member of the Academy familiar with the professional career of the deceased. For historical and bibliographical purposes, these volumes are worth returning to time and again. %0 Book %A National Academy of Sciences %E Ayala, Francisco J. %E Fitch, Walter M. %E Clegg, Michael T. %T Variation and Evolution in Plants and Microorganisms: Toward a New Synthesis 50 Years After Stebbins %@ 978-0-309-07099-7 %D 2000 %U https://nap.nationalacademies.org/catalog/9766/variation-and-evolution-in-plants-and-microorganisms-toward-a-new %> https://nap.nationalacademies.org/catalog/9766/variation-and-evolution-in-plants-and-microorganisms-toward-a-new %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %P 352 %X "The present book is intended as a progress report on [the] synthetic approach to evolution as it applies to the plant kingdom." With this simple statement, G. Ledyard Stebbins formulated the objectives of Variation and Evolution in Plants, published in 1950, setting forth for plants what became known as the "synthetic theory of evolution" or "the modern synthesis." The pervading conceit of the book was the molding of Darwin's evolution by natural selection within the framework of rapidly advancing genetic knowledge. At the time, Variation and Evolution in Plants significantly extended the scope of the science of plants. Plants, with their unique genetic, physiological, and evolutionary features, had all but been left completely out of the synthesis until that point. Fifty years later, the National Academy of Sciences convened a colloquium to update the advances made by Stebbins. This collection of 17 papers marks the 50th anniversary of the publication of Stebbins' classic. Organized into five sections, the book covers: early evolution and the origin of cells, virus and bacterial models, protoctist models, population variation, and trends and patterns in plant evolution. %0 Book %A National Research Council %T Scientific and Medical Aspects of Human Reproductive Cloning %@ 978-0-309-07637-1 %D 2002 %U https://nap.nationalacademies.org/catalog/10285/scientific-and-medical-aspects-of-human-reproductive-cloning %> https://nap.nationalacademies.org/catalog/10285/scientific-and-medical-aspects-of-human-reproductive-cloning %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %K Health and Medicine %P 294 %X Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would be—or would not be—acceptable to individuals or society. %0 Book %T (NAS Colloquium) Computational Biomolecular Science %D 1998 %U https://nap.nationalacademies.org/catalog/6239/nas-colloquium-computational-biomolecular-science %> https://nap.nationalacademies.org/catalog/6239/nas-colloquium-computational-biomolecular-science %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %K %P 107 %0 Book %A Institute of Medicine %T Advances in Understanding Genetic Changes in Cancer: Impact on Diagnosis and Treatment Decisions in the 1990s %@ 978-0-309-04688-6 %D 1992 %U https://nap.nationalacademies.org/catalog/1965/advances-in-understanding-genetic-changes-in-cancer-impact-on-diagnosis %> https://nap.nationalacademies.org/catalog/1965/advances-in-understanding-genetic-changes-in-cancer-impact-on-diagnosis %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 96 %X The past 20 years have seen a rapid increase in our understanding of the biology of cancer. And, advances in understanding the genetics of cancer are beginning to have an impact on the clinical management of malignant disease. Many of the genetic changes that underlie malignant transformation of cells and/or that distinguish malignant clones can be used as markers to diagnose, monitor, or characterize various forms of cancer. The purpose of this volume is to assess the current status of genetic testing in cancer management both from the standpoint of those tests and genetic markers that are presently available and from the perspective of genetic approaches to cancer testing that are likely to have an impact on cancer management in the near future. %0 Book %E Fitch, Walter M. %E Ayala, Francisco J. %T Tempo and Mode in Evolution: Genetics and Paleontology 50 Years After Simpson %@ 978-0-309-05191-0 %D 1995 %U https://nap.nationalacademies.org/catalog/4910/tempo-and-mode-in-evolution-genetics-and-paleontology-50-years %> https://nap.nationalacademies.org/catalog/4910/tempo-and-mode-in-evolution-genetics-and-paleontology-50-years %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %P 336 %X Since George Gaylord Simpson published Tempo and Mode in Evolution in 1944, discoveries in paleontology and genetics have abounded. This volume brings together the findings and insights of today's leading experts in the study of evolution, including Ayala, W. Ford Doolittle, and Stephen Jay Gould. The volume examines early cellular evolution, explores changes in the tempo of evolution between the Precambrian and Phanerozoic periods, and reconstructs the Cambrian evolutionary burst. Long-neglected despite Darwin's interest in it, species extinction is discussed in detail. Although the absence of data kept Simpson from exploring human evolution in his book, the current volume covers morphological and genetic changes in human populations, contradicting the popular claim that all modern humans descend from a single woman. This book discusses the role of molecular clocks, the results of evolution in 12 populations of Escherichia coli propagated for 10,000 generations, a physical map of Drosophila chromosomes, and evidence for "hitchhiking" by mutations. %0 Book %T Chemical Communication in a Post-Genomic World %D 2003 %U https://nap.nationalacademies.org/catalog/10965/chemical-communication-in-a-post-genomic-world %> https://nap.nationalacademies.org/catalog/10965/chemical-communication-in-a-post-genomic-world %I The National Academies Press %C Washington, DC %G English %K Math, Chemistry, and Physics %K Biology and Life Sciences %P 98 %X One major goal of post-genomic biology is to understand the function of genes. Many gene functions are comprehensible only within the context of chemical communication, and this symposium seeks to highlight emerging research on genomics and chemical communication and catalyze further development of this highly productive interface. Many of the most abundantly represented genes in the genomes characterized to date encode proteins mediating interactions among organisms, including odorant receptors and binding proteins, enzymes involved in biosynthesis of pheromones and toxins, and enzymes catalyzing the detoxification of defense compounds. Determining the molecular underpinnings of the component elements of chemical communication systems in all of their forms has the potential to explain a vast array of ecological, physiological, and evolutionary phenomena; by the same token, ecologists who elucidate the environmental challenges faced by the organisms are uniquely well-equipped to characterize natural ligands for receptors and substrates for enzymes. Thus, partnerships between genome biologists and chemical ecologists will likely be extremely synergistic. To date, these groups have rarely had opportunities to interact within a single forum. Such interactions are vital given the considerable practical benefits potentially stemming from these studies, including the development of biorational products for agricultural and forest pest management, for disease treatment, and for improving the quality of ecosystem health. %0 Book %A National Academy of Sciences %T Biographical Memoirs: Volume 46 %@ 978-0-309-02240-8 %D 1975 %U https://nap.nationalacademies.org/catalog/569/biographical-memoirs-volume-46 %> https://nap.nationalacademies.org/catalog/569/biographical-memoirs-volume-46 %I The National Academies Press %C Washington, DC %G English %K Biography and Autobiography %P 446 %X Biographic Memoirs: Volume 46 contains the biographies of deceased members of the National Academy of Sciences and bibliographies of their published works. Each biographical essay was written by a member of the Academy familiar with the professional career of the deceased. For historical and bibliographical purposes, these volumes are worth returning to time and again. %0 Book %A National Academy of Sciences %E Striedter, Georg F. %E Avise, John C. %E Ayala, Francisco J. %T In the Light of Evolution: Volume VI: Brain and Behavior %@ 978-0-309-26175-3 %D 2013 %U https://nap.nationalacademies.org/catalog/13462/in-the-light-of-evolution-volume-vi-brain-and-behavior %> https://nap.nationalacademies.org/catalog/13462/in-the-light-of-evolution-volume-vi-brain-and-behavior %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %P 430 %X The central goal of the In the Light of Evolution (ILE) series is to promote the evolutionary sciences through state-of-the-art colloquia--in the series of Arthur M. Sackler colloquia sponsored by the National Academy of Sciences--and their published proceedings. Each installment explores evolutionary perspectives on a particular biological topic that is scientifically intriguing but also has special relevance to contemporary societal issues or challenges. This book is the outgrowth of the Arthur M. Sackler Colloquium "Brain and Behavior," which was sponsored by the National Academy of Sciences on January 20-21, 2012, at the Academy's Arnold and Mabel Beckman Center in Irvine, CA. It is the sixth in a series of Colloquia under the general title "In the Light of Evolution." Specifically, In Light of Evolution: Brain and Behavior focuses on the field of evolutionary neuroscience that now includes a vast array of different approaches, data types, and species. This volume is also available for purchase with the In the Light of Evolution six-volume set. %0 Book %A National Academies of Sciences, Engineering, and Medicine %T The Chemistry of Microbiomes: Proceedings of a Seminar Series %@ 978-0-309-45836-8 %D 2017 %U https://nap.nationalacademies.org/catalog/24751/the-chemistry-of-microbiomes-proceedings-of-a-seminar-series %> https://nap.nationalacademies.org/catalog/24751/the-chemistry-of-microbiomes-proceedings-of-a-seminar-series %I The National Academies Press %C Washington, DC %G English %K Math, Chemistry, and Physics %P 132 %X The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine’s Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this “chemical dark matter” and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystems—earth, marine, and human—and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars. %0 Book %T (NAS Colloquium) Neuroimaging of Human Brain Function %@ 978-0-309-06027-1 %D 1998 %U https://nap.nationalacademies.org/catalog/6236/nas-colloquium-neuroimaging-of-human-brain-function %> https://nap.nationalacademies.org/catalog/6236/nas-colloquium-neuroimaging-of-human-brain-function %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %K Biology and Life Sciences %P 166 %X The colloquium on "Imaging of Cognitive Function" speaks to the many audiences whose interests relate to efforts to map cognitive processes in the human brain. There are things of great interest in this collection of papers for specialists in cognition and neuroscience and imaging science as well as in disciplines interested in human development through education and training and others with intrinsic interest in the latest information on how the human brain supports thought. The papers were presented at a meeting sponsored by the National Academy of Sciences in its western home the Beckman Center at the University of California, Irvine. %0 Book %A National Academy of Sciences %T Biographical Memoirs: Volume 59 %@ 978-0-309-04198-0 %D 1990 %U https://nap.nationalacademies.org/catalog/1652/biographical-memoirs-volume-59 %> https://nap.nationalacademies.org/catalog/1652/biographical-memoirs-volume-59 %I The National Academies Press %C Washington, DC %G English %K Biography and Autobiography %P 494 %X Biographic Memoirs: Volume 59 contains short biographies of deceased members of the National Academy of Sciences. %0 Book %A National Academy of Sciences %T Biographical Memoirs: Volume 62 %@ 978-0-309-04782-1 %D 1993 %U https://nap.nationalacademies.org/catalog/2201/biographical-memoirs-volume-62 %> https://nap.nationalacademies.org/catalog/2201/biographical-memoirs-volume-62 %I The National Academies Press %C Washington, DC %G English %K Biography and Autobiography %P 512 %X Biographic Memoirs: Volume 62 contains the biographies of deceased members of the National Academy of Sciences and bibliographies of their published works. Each biographical essay was written by a member of the Academy familiar with the professional career of the deceased. For historical and bibliographical purposes, these volumes are worth returning to time and again.