%0 Book %A Institute of Medicine %E Yaktine, Ann L. %E Pool, Robert %T Nutrigenomics and Beyond: Informing the Future: Workshop Summary %@ 978-0-309-10489-0 %D 2007 %U https://nap.nationalacademies.org/catalog/11845/nutrigenomics-and-beyond-informing-the-future-workshop-summary %> https://nap.nationalacademies.org/catalog/11845/nutrigenomics-and-beyond-informing-the-future-workshop-summary %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %K Food and Nutrition %P 90 %X The integration of biology, genomics, and health has opened the possibility of applying genomics technology to nutrition. In 2001, scientists associated with the Human Genome Project announced the successful mapping of the reference sequence of the human genome. Since then, a body of information has emerged. Genomics and related areas of research have contributed greatly to efforts to understand the cellular and molecular mechanisms underlying diet-disease relationships. Integration and application of genetic and genomics technology into nutrition research is, therefore, needed to develop nutrition research programs that are aimed at the prevention and control of chronic disease through genomics-based nutritional interventions. Of interest is the integration of relevant computational methods into nutritional genomics research; the enhancement of tools applicable to systems biology; and the effective dissemination of genomics-derived information to scientists, policy makers, and the interested public. To address these issues, a workshop was held on June 1 and 2, 2006. The workshop included presentations that were structured around three focus sessions: human genetic variation, epigenetics, and systems biology. A fourth session presented discussions on the implications of nutrigenomics for the future of nutrition science research. Numerous themes emerged from the workshop presentations. First, nutrigenomics is a complex field because it addresses issues related to multigenetic traits that can be modified by a number of nutritional and other environmental factors. Such complexity presents a challenge to the field; and the ensuing research opportunities will require cooperative work among scientific disciplines and across government, academic, and industrial centers, as well as adequate funding, to be realized. Additionally, the ability to stretch the limits of conventional research methodologies afforded by new genetic and genomic applications at the level of the individual opens the door to a wealth of potential benefits to areas such as disease prevention and wellness, bearing in mind the necessity of ethical safeguards. This potential, however, must be wisely exploited to avoid the pitfalls of overpromising research results and prematurely setting unrealistic expectations for beneficial outcomes. Finally, careful and rigorous research must be employed to optimize outcomes and assure acceptance by the scientific community. In summary, nutrition science is uniquely poised to serve as the crossroads for many disciplines and, using genomics tools, can bring this knowledge together to better understand and address diet-related chronic diseases and molecular responses to dietary factors. %0 Book %T Geologic Mapping in the U.S. Geological Survey %D 1987 %U https://nap.nationalacademies.org/catalog/11161/geologic-mapping-in-the-us-geological-survey %> https://nap.nationalacademies.org/catalog/11161/geologic-mapping-in-the-us-geological-survey %I The National Academies Press %C Washington, DC %G English %K Earth Sciences %P 32 %0 Book %A National Research Council %T Enhancing NASA's Contributions to Polar Science: A Review of Polar Geophysical Data Sets %@ 978-0-309-07401-8 %D 2001 %U https://nap.nationalacademies.org/catalog/10083/enhancing-nasas-contributions-to-polar-science-a-review-of-polar %> https://nap.nationalacademies.org/catalog/10083/enhancing-nasas-contributions-to-polar-science-a-review-of-polar %I The National Academies Press %C Washington, DC %G English %K Earth Sciences %P 138 %X The high latitudes of the Arctic and Antarctic, together with some mountainous areas with glaciers and long-lasting snow, are sometimes called the cryosphere-defined as that portion of the planet where water is perennially or seasonally frozen as sea ice, snow cover, permafrost, ice sheets, and glaciers. Variations in the extent and characteristics of surface ice and snow in the high latitudes are of fundamental importance to global climate because of the amount of the sun's radiation that is reflected from these often white surfaces. Thus, the cryosphere is an important frontier for scientists seeking to understand past climate events, current weather, and climate variability. Obtaining the data necessary for such research requires the capability to observe and measure a variety of characteristics and processes exhibited by major ice sheets and large-scale patterns of snow and sea ice extent, and much of these data are gathered using satellites.As part of its efforts to better support the researchers studying the cryosphere and climate, the National Aeronautics and Space Administration (NASA)-using sophisticated satellite technology-measures a range of variables from atmospheric temperature, cloud properties, and aerosol concentration to ice sheet elevation, snow cover on land, and ocean salinity. These raw data are compiled and processed into products, or data sets, useful to scientists. These so-called "polar geophysical data sets" can then be studied and interpreted to answer questions related to atmosphere and climate, ice sheets, terrestrial systems, sea ice, ocean processes, and many other phenomena in the cryosphere. The goal of this report is to provide a brief review of the strategy, scope, and quality of existing polar geophysical data sets and help NASA find ways to make these products and future polar data sets more useful to researchers, especially those working on the global change questions that lie at the heart of NASA's Earth Science Enterprise. %0 Book %A National Research Council %T Levees and the National Flood Insurance Program: Improving Policies and Practices %@ 978-0-309-28290-1 %D 2013 %U https://nap.nationalacademies.org/catalog/18309/levees-and-the-national-flood-insurance-program-improving-policies-and %> https://nap.nationalacademies.org/catalog/18309/levees-and-the-national-flood-insurance-program-improving-policies-and %I The National Academies Press %C Washington, DC %G English %K Earth Sciences %P 274 %X The Federal Emergency Management Agency's (FEMA) Federal Insurance and Mitigation Administration (FIMA) manages the National Flood Insurance Program (NFIP), which is a cornerstone in the U.S. strategy to assist communities to prepare for, mitigate against, and recover from flood disasters. The NFIP was established by Congress with passage of the National Flood Insurance Act in 1968, to help reduce future flood damages through NFIP community floodplain regulation that would control development in flood hazard areas, provide insurance for a premium to property owners, and reduce federal expenditures for disaster assistance. The flood insurance is available only to owners of insurable property located in communities that participate in the NFIP. Currently, the program has 5,555,915 million policies in 21,881 communities3 across the United States. The NFIP defines the one percent annual chance flood (100-year or base flood) floodplain as a Special Flood Hazard Area (SFHA). The SFHA is delineated on FEMA's Flood Insurance Rate Maps (FIRM's) using topographic, meteorologic, hydrologic, and hydraulic information. Property owners with a federally back mortgage within the SFHAs are required to purchase and retain flood insurance, called the mandatory flood insurance purchase requirement (MPR). Levees and floodwalls, hereafter referred to as levees, have been part of flood management in the United States since the late 1700's because they are relatively easy to build and a reasonable infrastructure investment. A levee is a man-made structure, usually an earthen embankment, designed and constructed in accordance with sound engineering practices to contain, control, or divert the flow of water so as to provide protection from temporary flooding. A levee system is a flood protection system which consists of a levee, or levees, and associated structures, such as closure and drainage devices, which are constructed and operated in accordance with sound engineering practices. Recognizing the need for improving the NFIP's treatment of levees, FEMA officials approached the National Research Council's (NRC) Water Science and Technology Board (WSTB) and requested this study. The NRC responded by forming the ad hoc Committee on Levee and the National Flood Insurance Program: Improving Policies and Practices, charged to examine current FEMA treatment of levees within the NFIP and provide advice on how those levee-elated policies and activities could be improved. The study addressed four broad areas, risk analysis, flood insurance, risk reduction, and risk communication, regarding how levees are considered in the NFIP. Specific issues within these areas include current risk analysis and mapping procedures behind accredited and non-accredited levees, flood insurance pricing and the mandatory flood insurance purchase requirement, mitigation options to reduce risk for communities with levees, flood risk communication efforts, and the concept of shared responsibility. The principal conclusions and recommendations are highlighted in this report. %0 Book %A National Research Council %T Assessment of Proposed Partnerships to Implement a National Landslide Hazards Mitigation Strategy: Interim Report %@ 978-0-309-08489-5 %D 2002 %U https://nap.nationalacademies.org/catalog/10431/assessment-of-proposed-partnerships-to-implement-a-national-landslide-hazards-mitigation-strategy %> https://nap.nationalacademies.org/catalog/10431/assessment-of-proposed-partnerships-to-implement-a-national-landslide-hazards-mitigation-strategy %I The National Academies Press %C Washington, DC %G English %K Earth Sciences %P 33 %X Landslides are a component of those agents of nature that transport rock and soil from mountains or hillsides to streams, lakes and seas, where new sedimentary rocks begin to form. Therefore, as well as destructive forces that can be induced by human activity, landslides are part of the earth's natural cyclic process of uplift, erosion, and sedimentation. With the growth of human population and the increasing habitation of ever-steeper slopes and higher altitudes, Man is both experiencing the effects of landslides and causing landslides with increasing frequency. These adverse effects include loss of life, injury, and damage to public and private works, as well as environmental damage. Accordingly, it is an opportune time to address the hazard posed by landslides, and to assess strategies to mitigate that hazard. Assessment of Proposed Partnerships to Implement a National Landslide Hazards Mitigation Strategy: Interim Reports is an interim statement addressing the U.S. Geological Survey's proposal for a national landslide hazards mitigation strategy. The scope of this interim report is constrained to assessing whether all the partners necessary for such a national strategy have been identified by the proposal—conclusions and recommendations to address the remainder of the statement of task will be presented in the committee's final report (e.g., will include comments regarding effective partnership implementation; funding strategies required for an effective mitigation program; and the balance between different components of a national strategy). In addition, in this interim report the committee offers a number of comments intended as interim guidance for the U.S. Geological Survey as it continues to plan a national strategy. %0 Book %A National Research Council %E Platt, Rutherford H. %T To Burn or Not to Burn: Summary of the Forum on Urban/Wildland Fire, January 26, 2001, Washington, DC %D 2001 %U https://nap.nationalacademies.org/catalog/10173/to-burn-or-not-to-burn-summary-of-the-forum %> https://nap.nationalacademies.org/catalog/10173/to-burn-or-not-to-burn-summary-of-the-forum %I The National Academies Press %C Washington, DC %G English %K Earth Sciences %P 18 %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Nicholson, Anna %E Snair, Justin %T Preparing for the Future of Disaster Health Volunteerism: Proceedings of a Workshop—in Brief %D 2017 %U https://nap.nationalacademies.org/catalog/24859/preparing-for-the-future-of-disaster-health-volunteerism-proceedings-of %> https://nap.nationalacademies.org/catalog/24859/preparing-for-the-future-of-disaster-health-volunteerism-proceedings-of %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %K Conflict and Security Issues %P 9 %X On April 26, 2017, the Forum on Medical and Public Health Preparedness for Disasters and Emergencies convened a workshop during a 4-hour session of the 2017 Preparedness Summit. Participants discussed potential characteristics of society in the year 2042 and the key resources, tools, and opportunities necessary to support the development of a robust, scalable, and regularly engaged disaster health volunteer workforce prepared for such a future. This publication summarizes the presentations and discussions from the workshop. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %E Shane, Jennifer %E Strong, Kelly %E Gransberg, Douglas %T Guide to Project Management Strategies for Complex Projects %D 2013 %U https://nap.nationalacademies.org/catalog/22755/guide-to-project-management-strategies-for-complex-projects %> https://nap.nationalacademies.org/catalog/22755/guide-to-project-management-strategies-for-complex-projects %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 0 %X TRB’s second Strategic Highway Research Program (SHRP 2) Report S2-R10-RW-2: Guide to Project Management Strategies for Complex Projects facilitates the application of a five-dimensional management approach for complex projects. The objective of the guide is to identify and communicate the critical factors involved in successfully managing complex transportation design and construction projects. A training course based on the information in the guide was also developed.In addition, SHRP 2 Renewal Project R10 developed two other reports:Project Management Strategies for Complex Projects, which describes the five-dimensional management approach for complex projects. The goal of the five-dimensional approach is to identify issues that should be planned and managed proactively, rather than retroactively. The five areas of the new project management approach address cost, schedule, engineering requirements, external influences, and financing; andProject Management Strategies for Complex Projects: Case Study Report, which includes case studies of 15 projects in the United States and three international projects that used tools that aid project managers in the delivery of complex projects.Software Disclaimer: This software is offered as is, without warranty or promise of support of any kind either expressed or implied. Under no circumstance will the National Academy of Sciences or the Transportation Research Board (collectively "TRB") be liable for any loss or damage caused by the installation or operation of this product. TRB makes no representation or warranty of any kind, expressed or implied, in fact or in law, including without limitation, the warranty of merchantability or the warranty of fitness for a particular purpose, and shall not in any case be liable for any consequential or special damages. %0 Book %A National Research Council %T Report of the Committee on Mapping and Sequencing the Human Genome %D 1988 %U https://nap.nationalacademies.org/catalog/18430/report-of-the-committee-on-mapping-and-sequencing-the-human-genome %> https://nap.nationalacademies.org/catalog/18430/report-of-the-committee-on-mapping-and-sequencing-the-human-genome %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %P 111 %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Khosla, Pradeep K. %E Beaton, Paul %T An Assessment of ARPA-E: Summary %D 2017 %U https://nap.nationalacademies.org/catalog/24811/an-assessment-of-arpa-e-summary %> https://nap.nationalacademies.org/catalog/24811/an-assessment-of-arpa-e-summary %I The National Academies Press %C Washington, DC %G English %K Policy for Science and Technology %P 44 %X In 2005, the National Research Council report Rising Above the Gathering Storm recommended a new way for the federal government to spur technological breakthroughs in the energy sector. It recommended the creation of a new agency, the Advanced Research Projects Agency-Energy, or ARPA-E, as an adaptation of the Defense Advanced Research Projects Agency (DARPA) model—widely considered a successful experiment that has funded out-of-the-box, transformative research and engineering that made possible the Internet, GPS, and stealth aircraft. This new agency was envisioned as a means of tackling the nation’s energy challenges in a way that could translate basic research into technological breakthroughs while also addressing economic, environmental, and security issues. Congress authorized ARPA-E in the 2007 America COMPETES Act and requested an early assessment following 6 years of operation to examine the agency’s progress toward achieving its statutory mission and goals. This publication summarizes the results of that assessment. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %E Governments, Rogue Valley Council of %T The Rogue Valley Ecological Framework: Mapping Open Space, Ecologically Important Areas, and Ecological Corridors for Transportation Planners, Agencies, Municipalities, Developers, Conservation NGOs, and Citizens %D 2013 %U https://nap.nationalacademies.org/catalog/22492/the-rogue-valley-ecological-framework-mapping-open-space-ecologically-important-areas-and-ecological-corridors-for-transportation-planners-agencies-municipalities-developers-conservation-ngos-and-citizens %> https://nap.nationalacademies.org/catalog/22492/the-rogue-valley-ecological-framework-mapping-open-space-ecologically-important-areas-and-ecological-corridors-for-transportation-planners-agencies-municipalities-developers-conservation-ngos-and-citizens %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 0 %X TRB’s second Strategic Highway Research Program (SHRP 2) has released a report that describes the result of a pilot test of the first three steps of the nine-step Integrated Ecological Framework (IEF) in the Rogue Valley, Jackson County, Oregon. The first three steps of the process result in a regional ecosystem framework (REF), which was defined as an overlay of regional environmental, ecological, and archaeological data with planned and existing transportation infrastructure.The IEF was developed in SHRP 2 Projects C06A (Integration of Conservation, Highway Planning, and Environmental Permitting Using an Outcome-Based Ecosystem Approach) and C06B (Integration of Conservation, Highway Planning, and Environmental Permitting Through Development of an Outcome-Based Ecosystem-Scale Approach and Corresponding Credit System). The IEF is available on the Transportation for Communities—Advancing Projects through Partnerships (TCAPP) website. TCAPP is now known as PlanWorks.Other pilot tests were conducted in California, Colorado, and West Virginia. %0 Book %A National Research Council %T Using Remote Sensing in State and Local Government: Information for Management and Decision Making %@ 978-0-309-08863-3 %D 2003 %U https://nap.nationalacademies.org/catalog/10648/using-remote-sensing-in-state-and-local-government-information-for %> https://nap.nationalacademies.org/catalog/10648/using-remote-sensing-in-state-and-local-government-information-for %I The National Academies Press %C Washington, DC %G English %K Space and Aeronautics %K Engineering and Technology %P 111 %X Advances in spatial, spectral, and temporal resolution over the past several years have greatly expanded opportunities for practical applications of remote sensing data. To explore the implications of these possibilities, the NRC held a series of three workshops on different facets of remote sensing applications. This report is on the third of those workshops: the development and use of remote sensing data and information by state, local, and regional governments. The steering committee was asked to examine the opportunities, potential challenges, and policy issues associated with the application of remote sensing data in the public sector including approaches and procedures for government agencies to use such data and barriers to development and use of the applications. The resulting report is addressed primarily to non-technical managers and decisions makers at all levels of government below the federal level. %0 Book %A National Academy of Sciences %T Frontiers of Bioinformatics: Unsolved Problems and Challenges %@ 978-0-309-10029-8 %D 2005 %U https://nap.nationalacademies.org/catalog/11453/frontiers-of-bioinformatics-unsolved-problems-and-challenges %> https://nap.nationalacademies.org/catalog/11453/frontiers-of-bioinformatics-unsolved-problems-and-challenges %I The National Academies Press %C Washington, DC %G English %K Computers and Information Technology %K Health and Medicine %K Biology and Life Sciences %P 58 %0 Book %A National Research Council %T Role of Terrestrial Ecosystems in Global Change: A Plan for Action %D 1994 %U https://nap.nationalacademies.org/catalog/18688/role-of-terrestrial-ecosystems-in-global-change-a-plan-for %> https://nap.nationalacademies.org/catalog/18688/role-of-terrestrial-ecosystems-in-global-change-a-plan-for %I The National Academies Press %C Washington, DC %G English %K %K Environment and Environmental Studies %P 59 %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %E Martin, Steve %E Debbage, Keith %E Kvistad, Amy %E Bañez, Douglas %T Measuring and Understanding the Relationship Between Air Service and Regional Economic Development %D 2022 %U https://nap.nationalacademies.org/catalog/26682/measuring-and-understanding-the-relationship-between-air-service-and-regional-economic-development %> https://nap.nationalacademies.org/catalog/26682/measuring-and-understanding-the-relationship-between-air-service-and-regional-economic-development %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 149 %X Airport economic impact studies may accurately measure the activity that occurs on airport properties or is tied directly to airport operations (such as off-site parking and hotels that accommodate airline crew who overnight in a location), but they do not capture how air service supports business and employment throughout the region. The TRB Airport Cooperative Research Program's ACRP Web-Only Document 53: Measuring and Understanding the Relationship Between Air Service and Regional Economic Development provides airports and major regional stakeholders concerned with economic development with the information and tools necessary to understand and communicate the nexus between air service and regional employment. The Web-Only Document is supplemental to ACRP WebResource 12: Air Service Development and Regional Economic Activity. Supplemental to the Web-Only Document is a Case Study Compilation with the full versions of the 14 case studies performed as part of the project. %0 Book %A National Research Council %T Elevation Data for Floodplain Mapping %@ 978-0-309-10409-8 %D 2007 %U https://nap.nationalacademies.org/catalog/11829/elevation-data-for-floodplain-mapping %> https://nap.nationalacademies.org/catalog/11829/elevation-data-for-floodplain-mapping %I The National Academies Press %C Washington, DC %G English %K Earth Sciences %P 166 %X Floodplain maps serve as the basis for determining whether homes or buildings require flood insurance under the National Flood Insurance Program run by the Federal Emergency Management Agency (FEMA). Approximately $650 billion in insured assets are now covered under the program. FEMA is modernizing floodplain maps to better serve the program. However, concerns have been raised as to the adequacy of the base map information available to support floodplain map modernization. Elevation Data for Floodplain Mapping shows that there is sufficient two-dimensional base map imagery to meet FEMA's flood map modernization goals, but that the three-dimensional base elevation data that are needed to determine whether a building should have flood insurance are not adequate. This book makes recommendations for a new national digital elevation data collection program to redress the inadequacy. Policy makers; property insurance professionals; federal, local, and state governments; and others concerned with natural disaster prevention and preparedness will find this book of interest. %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Moss, Steven %E Zierler, Michael %T Toward Sequencing and Mapping of RNA Modifications: Proceedings of a Workshop–in Brief %D 2023 %U https://nap.nationalacademies.org/catalog/27149/toward-sequencing-and-mapping-of-rna-modifications-proceedings-of-a %> https://nap.nationalacademies.org/catalog/27149/toward-sequencing-and-mapping-of-rna-modifications-proceedings-of-a %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %P 12 %X One strategy cells use for regulation is modifying proteins, DNA, and RNA to control their structure, function, and stability. For years, research has focused on the reversible modifications to proteins and DNA. However, RNA can also be highly modified, and more than 170 types of modification to RNA have been identified so far. Current methods for mapping and sequencing RNA and its modifications - also known as the epitranscriptome - are limited, partly because available sequencing technologies can detect only a small number of them. This limits the understanding of different molecular processes and leaves a gap in knowledge related to human diseases and disorders. To address these limitations and develop a roadmap for the sequencing of RNA with the epitranscriptome, the National Academies of Sciences, Engineering, and Medicine convened an ad hoc committee to provide a consensus report. A workshop held on March 14-15, 2023 was one part of an information-gathering effort by the committee and is summarized in this proceedings. %0 Book %A National Research Council %T Mapping and Sequencing the Human Genome %@ 978-0-309-07462-9 %D 1988 %U https://nap.nationalacademies.org/catalog/1097/mapping-and-sequencing-the-human-genome %> https://nap.nationalacademies.org/catalog/1097/mapping-and-sequencing-the-human-genome %I The National Academies Press %C Washington, DC %G English %K Biology and Life Sciences %P 128 %X There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers. %0 Book %A National Research Council %T Designing an Agricultural Genome Program %@ 978-0-309-06039-4 %D 1998 %U https://nap.nationalacademies.org/catalog/6081/designing-an-agricultural-genome-program %> https://nap.nationalacademies.org/catalog/6081/designing-an-agricultural-genome-program %I The National Academies Press %C Washington, DC %G English %K Agriculture %K Biology and Life Sciences %P 50 %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %T Prototype Software for an Environmental Information Management and Decision Support System %D 2007 %U https://nap.nationalacademies.org/catalog/23201/prototype-software-for-an-environmental-information-management-and-decision-support-system %> https://nap.nationalacademies.org/catalog/23201/prototype-software-for-an-environmental-information-management-and-decision-support-system %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 20 %X TRB’s National Cooperative Highway Research Program (NCHRP) Research Results Digest 317: Prototype Software for an Environmental Information Management and Decision Support System explores an effort to design, test, and demonstrate a prototype software program for an environmental information management system (EIMS) that state departments of transportation and others could use to support their environmental decision making throughout the transportation system management process. The EIMS is intended to serve as one component of an agency’s broader environmental management system (EMS). The project resulted in prototype software designed to support environmental management for transportation and planning agencies. The final report, including a user’s guide, is available as NCHRP Web-Only Document 103.Links to the download the EIMS software and to instructions on burning an .ISO CD-ROM are below.Help on Burning an .ISO CD-ROM ImageDownload the software as an .ISO Image(Warning: This file is large and may take some time to download)