%0 Book %A National Research Council %T Prospective Evaluation of Applied Energy Research and Development at DOE (Phase Two) %@ 978-0-309-10467-8 %D 2007 %U https://nap.nationalacademies.org/catalog/11806/prospective-evaluation-of-applied-energy-research-and-development-at-doe-phase-two %> https://nap.nationalacademies.org/catalog/11806/prospective-evaluation-of-applied-energy-research-and-development-at-doe-phase-two %I The National Academies Press %C Washington, DC %G English %K Energy and Energy Conservation %P 233 %X Since its inception in 1977 from an amalgam of federal authorities, the U.S. Department of Energy (DOE) has administered numerous programs aimed at developing applied energy technologies. In recent years, federal oversight of public expenditures has emphasized the integration of performance and budgeting. Notably, the Government Performance and Results Act (GPRA) was passed in 1993 in response to questions about the value and effectiveness of federal programs. GPRA and other mandates have led agencies to develop indicators of program performance and program outcomes. The development of indicators has been watched with keen interest by Congress, which has requested of the National Research Council (NRC) a series of reports using quantitative indicators to evaluate the effectiveness of applied energy research and development (R&D). The first such report took a retrospective view of the first 3 years of DOE R&D programs on fossil energy and energy efficiency. The report found that DOE-sponsored research had netted large commercial successes, such as advanced refrigerator compressors, electronic lighting ballasts, and emission control technology for flue gas desulfurization. However, some programs were judged to be costly failures in which large R&D expenditures did not result in a commercial energy technology. A follow-up NRC committee was assigned the task of adapting the methodology to the assessment of the future payoff of continuing programs. Evaluating the outcome of R&D expenditures requires an analysis of program costs and benefits. Doing so is not a trivial matter. First, the analysis of costs and benefits must reflect the full range of public benefits that are envisioned, accounting for environmental and energy security impacts as well as economic effects. Second, the analysis must consider how likely the research is to succeed and how valuable the research will be if successful. Finally, the analysis must consider what might happen if the government did not support the project: Would some non-DOE entity undertake it or an equivalent activity that would produce some or all of the benefits of government involvement? This second report continues to investigate the development and use of R&D outcome indicators and applies the benefits evaluation methodology to six DOE R&D activities. It provides further definition for the development of indicators for environmental and security benefits and refines the evaluation process based on its experience with the six DOE R&D case studies. %0 Book %A National Research Council %T Prospective Evaluation of Applied Energy Research and Development at DOE (Phase One): A First Look Forward %@ 978-0-309-09604-1 %D 2005 %U https://nap.nationalacademies.org/catalog/11277/prospective-evaluation-of-applied-energy-research-and-development-at-doe-phase-one %> https://nap.nationalacademies.org/catalog/11277/prospective-evaluation-of-applied-energy-research-and-development-at-doe-phase-one %I The National Academies Press %C Washington, DC %G English %K Energy and Energy Conservation %P 138 %X In 2001, the National Research Council (NRC) completed a congressionally mandated assessment of the benefits and costs of DOE's fossil energy and energy efficiency R&D programs, Energy Research at DOE: Was It Worth It? The Congress followed this retrospective study by directing DOE to request the NRC to develop a methodology for assessing prospective benefits. The first phase of this project—development of the methodology—began in December 2003. Phase two will make the methodology more robust and explore related issues, and subsequent phases will apply the methodology to review the prospective benefits of different DOE fossil energy and energy efficiency R&D programs. In developing this project, three considerations were particularly important. First, the study should adapt the work of the retrospective study. Second, the project should develop a methodology that provides a rigorous calculation of benefits and risks, and a practical and consistent process for its application. Third, the methodology should be transparent, should not require extensive resources for implementation, and should produce easily understood results. This report presents the results of phase one. It focuses on adaptation of the retrospective methodology to a prospective context. %0 Book %A National Research Council %T Review of DOE's Vision 21 Research and Development Program: Phase I %@ 978-0-309-08717-9 %D 2003 %U https://nap.nationalacademies.org/catalog/10596/review-of-does-vision-21-research-and-development-program-phase %> https://nap.nationalacademies.org/catalog/10596/review-of-does-vision-21-research-and-development-program-phase %I The National Academies Press %C Washington, DC %G English %K Energy and Energy Conservation %P 108 %X The Vision 21 Program is a relatively new research and development (R&D) program. It is funded through the U.S. Department of Energy's (DOE's) Office of Fossil Energy and its National Energy Technology Laboratory (NETL). The Vision 21 Program Plan anticipates that Vision 21 facilities will be able to convert fossil fuels (e.g., coal, natural gas, and petroleum coke) into electricity, process heat, fuels, and/or chemicals cost effectively, with very high efficiency and very low emissions, including of the greenhouse gas carbon dioxide (CO2). The goals of Vision 21 are extremely challenging and ambitious. As noted in the Vision 21 Technology Roadmap, if the program meets its goals, Vision 21 plants would essentially eliminate many of the environmental concerns traditionally associated with the conversion of fossil fuels into electricity and transportation fuels or chemicals (NETL, 2001). Given the importance of fossil fuels, and especially coal, to the economies of the United States and other countries and the need to utilize fossil fuels in an efficient and environmentally acceptable manner, the development of the technologies in the Vision 21 Program is a high priority.This report contains the results of the second National Research Council (NRC) review of the Vision 21 R&D Program. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %T Producing Transportation Data Products from the American Community Survey That Comply With Disclosure Rules %D 2011 %U https://nap.nationalacademies.org/catalog/18160/producing-transportation-data-products-from-the-american-community-survey-that-comply-with-disclosure-rules %> https://nap.nationalacademies.org/catalog/18160/producing-transportation-data-products-from-the-american-community-survey-that-comply-with-disclosure-rules %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 386 %X TRB’s National Cooperative Highway Research Program (NCHRP) Web-Only Document 180: Producing Transportation Data Products from the American Community Survey That Comply With Disclosure Rules explores approaches to apply data perturbation techniques that will provide Census Transportation Planning Products data users complete tables that are accurate enough to support transportation planning applications, but that also are modified enough that the Disclosure Review Board is satisfied that they prevent effective data snooping. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %E Company, Inc. Burns & McDonnell Engineering %T Rebranding TCAPP to PlanWorks %D 2014 %U https://nap.nationalacademies.org/catalog/22323/rebranding-tcapp-to-planworks %> https://nap.nationalacademies.org/catalog/22323/rebranding-tcapp-to-planworks %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 0 %X TRB’s second Strategic Highway Research Program (SHRP 2) Capacity Project C37 has released the final report: Rebranding TCAPP to PlanWorks. TCAPP, which stands for Transportation for Communities—Advancing Projects through Partnerships, is a web portal designed to support collaborative decision making in the transportation planning and project development process. In late 2012, with the research and development phase of TCAPP substantially completed, it was determined that the name TCAPP should be rebranded. The report reviews market research associated with rebranding and presents the research team’s conclusions about rebranding. The report contains seven appendices that provide additional marketing information developed as a part of this project. %0 Book %A Institute of Medicine %A National Academy of Engineering %E Madhavan, Guruprasad %E Phelps, Charles %E Rappuoli, Rino %E Martinez, Rose Marie %E King, Lonnie %T Ranking Vaccines: Applications of a Prioritization Software Tool: Phase III: Use Case Studies and Data Framework %@ 978-0-309-30403-0 %D 2015 %U https://nap.nationalacademies.org/catalog/18763/ranking-vaccines-applications-of-a-prioritization-software-tool-phase-iii %> https://nap.nationalacademies.org/catalog/18763/ranking-vaccines-applications-of-a-prioritization-software-tool-phase-iii %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 128 %X SMART Vaccines - Strategic Multi-Attribute Ranking Tool for Vaccines - is a prioritization software tool developed by the Institute of Medicine that utilizes decision science and modeling to help inform choices among candidates for new vaccine development. A blueprint for this computer-based guide was presented in the 2012 report Ranking Vaccines: A Prioritization Framework: Phase I. The 2013 Phase II report refined a beta version of the model developed in the Phase I report. Ranking Vaccines: Applications of a Prioritization Software Tool: Phase III: Use Case Studies and Data Framework extends this project by demonstrating the practical applications of SMART Vaccines through use case scenarios in partnership with the Public Health Agency of Canada, New York State Department of Health, and the Serum Institute of India. This report also explores a novel application of SMART Vaccines in determining new vaccine product profiles, and offers practical strategies for data synthesis and estimation to encourage the broader use of the software. %0 Book %A Institute of Medicine %E Madhavan, Guruprasad %E Sangha, Kinpritma %E Phelps, Charles %E Fryback, Dennis %E Rappuoli, Rino %E Martinez, Rose Marie %E King, Lonnie %T Ranking Vaccines: A Prioritization Software Tool: Phase II: Prototype of a Decision-Support System %@ 978-0-309-26638-3 %D 2013 %U https://nap.nationalacademies.org/catalog/13531/ranking-vaccines-a-prioritization-software-tool-phase-ii-prototype-of %> https://nap.nationalacademies.org/catalog/13531/ranking-vaccines-a-prioritization-software-tool-phase-ii-prototype-of %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 160 %X SMART Vaccines—Strategic Multi-Attribute Ranking Tool for Vaccines—is a prioritization software tool developed by the Institute of Medicine that utilizes decision science and modeling to help inform choices among candidates for new vaccine development. A blueprint for this computer-based guide was presented in the 2012 report Ranking Vaccines: A Prioritization Framework: Phase I. Ranking Vaccines: A Prioritization Software Tool,Phase II extends the proof-of-concept presented in the Phase I report, which was based on multi-attribute utility theory. This report refines a beta version of the model developed in the Phase I report and presents its next iteration, SMART Vaccines 1.0. Ranking Vaccines: Phase II discusses the methods underlying the development, validation, and evaluation of SMART Vaccines 1.0. It also discusses how SMART Vaccines should—and, just as importantly, should not—be used. The report also offers ideas for future enhancements for SMART Vaccines as well as for ideas for expanded uses and considerations and possibilities for the future. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %E Flannagan, Carol A. %E Lyle, Jared %E Carlson, Jacob %E Bedford, Denise %T Developing a Guide to Ensuring Access to the Publications and Data of Federally Funded Transportation Research %D 2020 %U https://nap.nationalacademies.org/catalog/25855/developing-a-guide-to-ensuring-access-to-the-publications-and-data-of-federally-funded-transportation-research %> https://nap.nationalacademies.org/catalog/25855/developing-a-guide-to-ensuring-access-to-the-publications-and-data-of-federally-funded-transportation-research %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 57 %X The TRB National Cooperative Highway Research Program's NCHRP Web-Only Document 270: Developing a Guide to Ensuring Access to the Publications and Data of Federally Funded Transportation Research provides guidance for state departments of transportation (DOTs) to help them meet the requirements of the U.S. DOT Public Access Plan requiring preservation of the products of all federally funded transportation research.The document is released in parallel with NCHRP Research Report 936: Guide to Ensuring Access to the Publications and Data of Federally Funded Transportation Research. %0 Book %A National Academies of Sciences, Engineering, and Medicine %T Potential Hydrodynamic Impacts of Offshore Wind Energy on Nantucket Shoals Regional Ecology: An Evaluation from Wind to Whales %@ 978-0-309-70668-1 %D 2024 %U https://nap.nationalacademies.org/catalog/27154/potential-hydrodynamic-impacts-of-offshore-wind-energy-on-nantucket-shoals-regional-ecology %> https://nap.nationalacademies.org/catalog/27154/potential-hydrodynamic-impacts-of-offshore-wind-energy-on-nantucket-shoals-regional-ecology %I The National Academies Press %C Washington, DC %G English %K Energy and Energy Conservation %K Earth Sciences %P 120 %X The transition to renewable energy has spurred many efforts to scale up the U.S. portfolio of efficient clean energy resources, including the development of offshore wind farms. The Nantucket Shoals region off the coast of Massachusetts is the first large scale wind farm installation under development in U.S. waters. To ensure Nantucket Shoals region offshore wind energy installations are being planned, constructed, and developed in an environmentally responsible way, the Bureau of Ocean Energy Management (BOEM) asked the National Academies to evaluate the potential for offshore wind farms in the Nantucket Shoals region to affect oceanic physical processes, and, in turn, how those hydrodynamic alterations might affect local to regional ecosystems. Of particular interest to BOEM are the potential effects of hydrodynamic changes on zooplankton productivity and aggregations, which may affect foraging for the critically endangered North Atlantic right whale. This report found the impacts of offshore wind projects on the North Atlantic right whale and the availability of their prey in the Nantucket Shoals region will likely be difficult to distinguish from the significant impacts of climate change and other influences on the ecosystem. Further study and monitoring of the oceanography and ecology of the Nantucket Shoals region is needed to fully understand the impact of future wind farms. This report recommends the Bureau of Ocean Energy Management, the National Oceanic and Atmospheric Administration, and others should promote observational studies and modeling that will advance understanding of potential hydrodynamic effects and their consequent impacts on ecology in the Nantucket Shoals region during all phases of wind energy development. %0 Book %A National Academies of Sciences, Engineering, and Medicine %T Weapons System Sustainment Planning Early in the Development Life Cycle %@ 978-0-309-67585-7 %D 2020 %U https://nap.nationalacademies.org/catalog/25756/weapons-system-sustainment-planning-early-in-the-development-life-cycle %> https://nap.nationalacademies.org/catalog/25756/weapons-system-sustainment-planning-early-in-the-development-life-cycle %I The National Academies Press %C Washington, DC %G English %K Conflict and Security Issues %P 98 %X According to the Government Accountability Office, sustainment of weapon systems accounts for approximately 70 percent of the total life-cycle costs. When sustainment is not considered early in the development process or as an integral part of the systems engineering design, it can negatively affect the ability of the Air Force to maintain and improve the weapon system once it enters service. At the request of the Assistant Secretary of the Air Force for Acquisition, Technology, and Logistics, Weapons Systems Sustainment Planning Early in the Development Life Cycle identifies at what point or phase of the development of a weapons system sustainment planning should be integrated into the program; examines and provides recommendations regarding how sustainment planning should be evaluated throughout the development process; investigates and describes the current challenges with sustainment planning and determines what changes have occurred throughout the acquisition process that may have eroded sustainment planning; and identifies opportunities for acquisitions offices to gain greater access to sustainment expertise. %0 Book %A National Academies of Sciences, Engineering, and Medicine %E Khandekar, Eeshan %E Hackmann, Meredith %E Addie, Siobhan %E Nicholson, Anna %E Beachy, Sarah H. %E Shore, Carolyn %T The Role of Digital Health Technologies in Drug Development: Proceedings of a Workshop %@ 978-0-309-67959-6 %D 2020 %U https://nap.nationalacademies.org/catalog/25850/the-role-of-digital-health-technologies-in-drug-development-proceedings %> https://nap.nationalacademies.org/catalog/25850/the-role-of-digital-health-technologies-in-drug-development-proceedings %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 142 %X On March 24, 2020, a 1-day public workshop titled The Role of Digital Health Technologies in Drug Development was convened by the National Academies of Sciences, Engineering, and Medicine. This workshop builds on prior efforts to explore how virtual clinical trials facilitated by digital health technologies (DHTs) might change the landscape of drug development. To explore the challenges and opportunities in using DHTs for improving the probability of success in drug R&D, enabling better patient care, and improving precision medicine, the workshop featured presentations and panel discussions on the integration of DHTs across all phases of drug development. Throughout the workshop, participants considered how DHTs could be applied to achieve the greatest impact—and perhaps even change the face of how clinical trials are conducted—in ways that are also ethical, equitable, safe, and effective. This publication summarizes the presentations and discussions from the workshop. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %T Procedures Guide for Right-of-Way Cost Estimation and Cost Management %D 2009 %U https://nap.nationalacademies.org/catalog/14289/procedures-guide-for-right-of-way-cost-estimation-and-cost-management %> https://nap.nationalacademies.org/catalog/14289/procedures-guide-for-right-of-way-cost-estimation-and-cost-management %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 213 %X TRB’s National Cooperative Highway Research Program (NCHRP) Report 625: Procedures Guide for Right-of-Way Cost Estimation and Cost Management explores approaches for developing right-of-way (ROW) cost estimates. The report also examines ways to track and manage ROW cost during all phases of project development, including planning, programming, and preliminary and final design. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %E Connor, Robert J. %E Schroeder, Curtis J. %E Crowley, Bridget M. %E Washer, Glenn A. %E Fish, Philip E. %T Acceptance Criteria of Complete Joint Penetration Steel Bridge Welds Evaluated Using Enhanced Ultrasonic Methods %D 2019 %U https://nap.nationalacademies.org/catalog/25494/acceptance-criteria-of-complete-joint-penetration-steel-bridge-welds-evaluated-using-enhanced-ultrasonic-methods %> https://nap.nationalacademies.org/catalog/25494/acceptance-criteria-of-complete-joint-penetration-steel-bridge-welds-evaluated-using-enhanced-ultrasonic-methods %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 84 %X TRB’s National Cooperative Highway Research Program (NCHRP) Research Report 908: Acceptance Criteria of Complete Joint Penetration Steel Bridge Welds Evaluated Using Enhanced Ultrasonic Methods presents guidelines for evaluating complete joint penetration (CJP) welds in steel bridges and proposes modifications to the American Association of State Highway and Transportation Officials (AASHTO)/American Welding Society (AWS) D1.5.Inspection of welds in steel bridges is necessary to ensure the quality of workmanship during the fabrication and construction process and later on when the bridge is in service. There are two non-destructive evaluation (NDE) methods for evaluation of complete joint penetration (CJP) welds in steel bridges: radiographic (RT) and ultrasonic (UT). Recent advances in enhanced ultrasonic methods, including the development of phased-array ultrasonic technology (PAUT), allow for efficient detection and characterization of flaws with the option of automated data collection and imaging.Criteria for categorizing weld discontinuities as acceptable or unacceptable are codified in the AASHTO/AWS D1.5M/D1.5: Bridge Welding Code (BWC). However, these acceptance criteria do not reflect the full use of the capability of enhanced ultrasonic testing methods, and furthermore are not based on the effect of weld discontinuities on bridge performance (e.g., resistance to fatigue and fracture). In addition, some weld discontinuities that are not allowed according to BWC are potentially not harmful and may not decrease service life.An updated acceptance criteria based on enhanced ultrasonic testing methods for evaluation of CJP welds in steel bridges was needed for fabricators and bridge owners. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %E Quiroga, Cesar %E Kraus, Edgar %E Cochran, Lauren %T Practices for Utility Coordination in Transit Projects %D 2015 %U https://nap.nationalacademies.org/catalog/22172/practices-for-utility-coordination-in-transit-projects %> https://nap.nationalacademies.org/catalog/22172/practices-for-utility-coordination-in-transit-projects %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 55 %X TRB’s Transit Cooperative Research Program (TCRP) Synthesis 118: Practices for Utility Coordination in Transit Projects summarizes utility coordination practices at transit agencies around the country. Specifically, the report focuses on utility coordination issues that transit agencies undertake during typical phases of project development and delivery, including planning, designing, and constructing civil infrastructure facilities. %0 Book %A Institute of Medicine %E Beachy, Sarah H. %E Berger, Adam C. %E Olson, Steve %T Conflict of Interest and Medical Innovation: Ensuring Integrity While Facilitating Innovation in Medical Research: Workshop Summary %@ 978-0-309-30168-8 %D 2014 %U https://nap.nationalacademies.org/catalog/18723/conflict-of-interest-and-medical-innovation-ensuring-integrity-while-facilitating %> https://nap.nationalacademies.org/catalog/18723/conflict-of-interest-and-medical-innovation-ensuring-integrity-while-facilitating %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 98 %X Scientific advances such as the sequencing of the human genome have created great promise for improving human health by providing a greater understanding of disease biology and enabling the development of new drugs, diagnostics, and preventive services. However, the translation of research advances into clinical applications has so far been slower than anticipated. This is due in part to the complexity of the underlying biology as well as the cost and time it takes to develop a product. Pharmaceutical companies are adapting their business models to this new reality for product development by placing increasing emphasis on leveraging alliances, joint development efforts, early-phase research partnerships, and public-private partnerships. These collaborative efforts make it possible to identify new drug targets, enhance the understanding of the underlying basis of disease, discover novel indications for the use of already approved products, and develop biomarkers for disease outcomes or directed drug use. While the potential benefits of collaboration are significant, the fact that the relationships among development partners are often financial means that it is vital to ensure trust by identifying, disclosing, and managing any potential sources of conflict that could create bias in the research being performed together. Conflict of Interest and Medical Innovation is the summary of a workshop convened by the Institute of Medicine Roundtable on Translating Genomic-Based Research for Health in June 2013 to explore the appropriate balance between identifying and managing conflicts of interest and advancing medical innovation. A wide range of stakeholders, including government officials, pharmaceutical company representatives, academic administrators and researchers, health care providers, medical ethicists, patient advocates, and consumers, were invited to present their perspectives and participate in discussions during the workshop. This report focuses on current conflict of interest policies and their effect on medical innovation in an effort to identify best practices and potential solutions for facilitating innovation while still ensuring scientific integrity and public trust. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %T Strategies to Optimize Real Property Acquisition, Relocation Assistance, and Property Management Practices %D 2014 %U https://nap.nationalacademies.org/catalog/22252/strategies-to-optimize-real-property-acquisition-relocation-assistance-and-property-management-practices %> https://nap.nationalacademies.org/catalog/22252/strategies-to-optimize-real-property-acquisition-relocation-assistance-and-property-management-practices %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 201 %X TRB’s National Cooperative Highway Research Program (NCHRP) Report 771: Strategies to Optimize Real Property Acquisition, Relocation Assistance, and Property Management Practices provides improved, integrated real property procedures and business practices in the project development and delivery process. The report also provides suggestions to improve property management practices. The report is accompanied by a CD-ROM that contains an integrated model of the transportation project development and delivery process, including a real property acquisition and relocation assistance model and reference work schedule.The CD-ROM is also available for download from TRB’s website as an ISO image. Links to the ISO image and instructions for burning a CD-ROM from an ISO image are provided below.Help on Burning an .ISO CD-ROM ImageDownload the .ISO CD-ROM Image(Warning: This is a large file and may take some time to download using a high-speed connection.)CD-ROM Disclaimer - This software is offered as is, without warranty or promise of support of any kind either expressed or implied. Under no circumstance will the National Academy of Sciences or the Transportation Research Board (collectively "TRB") be liable for any loss or damage caused by the installation or operation of this product. TRB makes no representation or warranty of any kind, expressed or implied, in fact or in law, including without limitation, the warranty of merchantability or the warranty of fitness for a particular purpose, and shall not in any case be liable for any consequential or special damages. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %E Shane, Jennifer %E Strong, Kelly %E Gransberg, Douglas %E Ahn, Junyong %E Allan, Neil %E Brisk, Debra %E Hunt, James %E del Puerto, Carla Lopez %E John, Owens %E Scheepbouwer, Eric %E Scott, Sidney %E Tighe, Susan %E Touran, Ali %T Project Management Strategies for Complex Projects: Case Study Report %D 2014 %U https://nap.nationalacademies.org/catalog/22413/project-management-strategies-for-complex-projects-case-study-report %> https://nap.nationalacademies.org/catalog/22413/project-management-strategies-for-complex-projects-case-study-report %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 0 %X TRB’s second Strategic Highway Research Program (SHRP 2) Renewal Project R10 has released a report titled Project Management Strategies for Complex Projects: Case Study Report, which includes case studies of 15 projects in the United States and three international projects that used tools that aid project managers in the delivery of complex projects. The 18 projects represent a number of different types, locations, size, and phases of development. The tools identified fall into two areas—project development and project execution.In addition, SHRP 2 Renewal Project R10 developed two other reports:Project Management Strategies for Complex Projects, which describes the five-dimensional management approach for complex projects. The goal of the five-dimensional approach is to identify issues that should be planned and managed proactively, rather than retroactively. The five areas of the new project management approach address cost, schedule, engineering requirements, external influences, and financing; and Guide To: Project Management Strategies for Complex Projects, which is designed to help facilitate the application of the five-dimensional project management approach for complex projects. The objective of the guide is to identify and communicate the critical factors involved in successfully managing complex transportation design and construction projects. A training course based on the information in the guide was also developed. %0 Book %A Transportation Research Board %A National Academies of Sciences, Engineering, and Medicine %T Committee for a Study of Options for Streamlining Standards for Intelligent Transportation Systems Letter Report: June 18, 2007 %D 2007 %U https://nap.nationalacademies.org/catalog/22008/committee-for-a-study-of-options-for-streamlining-standards-for-intelligent-transportation-systems-letter-report-june-18-2007 %> https://nap.nationalacademies.org/catalog/22008/committee-for-a-study-of-options-for-streamlining-standards-for-intelligent-transportation-systems-letter-report-june-18-2007 %I The National Academies Press %C Washington, DC %G English %K Transportation and Infrastructure %P 0 %X TRB’s Committee for a Study of Options for Streamlining Standards for Intelligent Transportation Systems has delivered a letter report to Ms. Shelley Row, director of the U.S. Department of Transportation’s (USDOT’s) ITS Joint Program Office. The letter report examines the federal role in developing and deploying ITS standards. It recommends that USDOT continue to play a prominent role in support of ITS standards but one that is guided by a well-articulated strategic vision and program plan. USDOT is advised to engage users of standards in all phases of standards development and to become more active in international ITS standards activities. %0 Book %A Institute of Medicine %E Norris, Sheena M. Posey %E Pankevich, Diana E. %E Davis, Miriam %E Altevogt, Bruce M. %T Improving and Accelerating Therapeutic Development for Nervous System Disorders: Workshop Summary %@ 978-0-309-29246-7 %D 2014 %U https://nap.nationalacademies.org/catalog/18494/improving-and-accelerating-therapeutic-development-for-nervous-system-disorders-workshop %> https://nap.nationalacademies.org/catalog/18494/improving-and-accelerating-therapeutic-development-for-nervous-system-disorders-workshop %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 118 %X Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials. %0 Book %A Institute of Medicine %E Wizemann, Theresa %E Reeve, Megan %E Altevogt, Bruce %T Engaging the Public in Critical Disaster Planning and Decision Making: Workshop Summary %@ 978-0-309-28891-0 %D 2013 %U https://nap.nationalacademies.org/catalog/18396/engaging-the-public-in-critical-disaster-planning-and-decision-making %> https://nap.nationalacademies.org/catalog/18396/engaging-the-public-in-critical-disaster-planning-and-decision-making %I The National Academies Press %C Washington, DC %G English %K Health and Medicine %P 69 %X Engaging the Public in Critical Disaster Planning and Decision Making is the summary of a workshop held in March 2013 to discuss the key principles of public engagement during the development of disaster plans, the response phase, and during the dissemination phase when interested community partners and the general public are informed of the policies that have been adopted. Presenters provided specific examples of resources to assist jurisdictions in planning public engagement activities as well as challenges experienced and potential solutions. This report introduces key principles of public engagement, provides practical guidance on how to plan and implement a public engagement activity, and presents tools to facilitate planning.