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Microbial Status and Genetic Evaluation of Mice and Rats: Proceedings of the 1999 US/Japan Conference (2000)
Institute for Laboratory Animal Research (ILAR)

Page
149
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Microbial Status and Genetic Evaluation of Mice and Rats: PROCEEDINGS OF THE 1999 US/JAPAN CONFERENCE

Appendix B

Meeting Participants

Anton M. Allen, PhD, retired from National Institutes of Health

Jacqueline N. Crawley, PhD, National Institutes of Mental Health, Bethesda, MD

Joseph J. DeGeorge, PhD, Associate Director for Pharmacology and Toxicology, Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, MD

Michael F.W. Festing, PhD, CStat, MRC Toxicology Unit, University of Leicester, UK

Eugenia Floyd, DVM, Pfizer Central Research, Groton, CT

James Fox, DVM, Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA

Toshio Itoh, DVM, PhD, Deputy Director of ICLAS Monitoring Center, Central Institute for Experimental Animals, Kawasaki, Japan

Howard Jacob, PhD, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI

Dabney K. Johnson, PhD, Oak Ridge National Laboratory, Oak Ridge, TN

Naoko Kagiyama, DVM, PhD, Head of Laboratory Animal Services, Preclinical Department, Novartis Pharma K.K., Tsukuba Research Institute, Tsukuba, Japan

Hideki Katoh, PhD, Associate Professor, Laboratory Animal Research Center, Hamamatsu University, Hamamatsu, Japan

Kazuo Moriwaki, PhD, Vice President, The Graduate University for Advanced Sciences, Kanagawa-kenn, Japan

Page
149
Front Matter (R1-R16)
Opening Remarks, Judith Vaitukaitis (1-3)
Opening Remarks, Shin-Ichi Ota (4-5)
Introductory Comments on Microbiologic Testing of Laboratory Mice and Rats: Uniformity of Results (6-6)
Development of a Performance Assessment Program for Research Animal Diagnostic Laboratories and Defining Microbiologic Testing Standards (7-10)
Standardization of Rodent Health Surveillance: Regulation Versus Competition (11-15)
Factors Causing Difficulties in Uniformity of Results Among Testing Facilities in Microbiologic Monitoring of Laboratory Animals (16-20)
Necessity of Reexamining the Pathogenicity and Elimination of Parasites in Rats and Mice (21-26)
Emerging (and Reemerging) Viruses of Laboratory Mice and Rats (27-34)
Emerging Infections as a Cause of Concern (35-39)
Emerging Diseases in Mice and Rats (40-43)
Survey of Heliobacter Species in Laboratory Mice and Gerbils in Japan (44-46)
Genetic Evaluation of Outbred Rats (47-50)
Genetic Evaluation of Outbred Rats from the Breeder's Perspective (51-64)
Concept for Establishment of Rat Outbred Global Standard Strains (65-76)
Necessity of Genetic and Microbiologic Quality Network from the Pharmaceutical Industry's Perspective (77-84)
International Harmonization of Laboratory Animals (85-96)
Rat Genetics and Toxicology (97-104)
A Phenotype-driven Approach to the Molecular and Functional Analysis of the Mouse Genome (105-115)
Evaluation of Targeted Mutations (116-118)
Defining Behavioral Phenotypes in Transgenic and Knockout Mice (119-129)
Defining Phenotype in Genetically Engineered Mice (130-131)
Development of the Mouse Model Dramatype for Human Clinical Benefit (132-136)
Concluding Remarks (137-137)
Implication of Wild-derived Genes, Mitochondria, and Chromosomes in the Genetic Background of Mouse Models for Diseases and Biologic Functions (138-141)
Concluding Comments, John Strandberg (142-143)
Concluding Remarks, John Vandenbergh (144-146)
Appendix A (147-148)
Appendix B (149-150)

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OCR for page 149
Microbial Status and Genetic Evaluation of Mice and Rats: PROCEEDINGS OF THE 1999 US/JAPAN CONFERENCE Appendix B Meeting Participants Anton M. Allen, PhD, retired from National Institutes of Health Jacqueline N. Crawley, PhD, National Institutes of Mental Health, Bethesda, MD Joseph J. DeGeorge, PhD, Associate Director for Pharmacology and Toxicology, Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, MD Michael F.W. Festing, PhD, CStat, MRC Toxicology Unit, University of Leicester, UK Eugenia Floyd, DVM, Pfizer Central Research, Groton, CT James Fox, DVM, Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA Toshio Itoh, DVM, PhD, Deputy Director of ICLAS Monitoring Center, Central Institute for Experimental Animals, Kawasaki, Japan Howard Jacob, PhD, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI Dabney K. Johnson, PhD, Oak Ridge National Laboratory, Oak Ridge, TN Naoko Kagiyama, DVM, PhD, Head of Laboratory Animal Services, Preclinical Department, Novartis Pharma K.K., Tsukuba Research Institute, Tsukuba, Japan Hideki Katoh, PhD, Associate Professor, Laboratory Animal Research Center, Hamamatsu University, Hamamatsu, Japan Kazuo Moriwaki, PhD, Vice President, The Graduate University for Advanced Sciences, Kanagawa-kenn, Japan

OCR for page 150
Microbial Status and Genetic Evaluation of Mice and Rats: PROCEEDINGS OF THE 1999 US/JAPAN CONFERENCE Stephen Morse, PhD, Defense Sciences Office, Defense Advance Research Projects Agency, U.S. Department of Defense, Arlington, VA Kazunori Nakajima, MD, PhD, Department Head, Assistant Professor, Department of Molecular Neurobiology, Institute of DNA Medicine, Jikei University School of Medicine, Tokyo, Japan. Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Corporation (JST) Tatsuji Nomura, MD, PhD, Director, Central Institute for Experimental Animals, Kawasaki, Japan Shin-Ichi Ota, MA, Sci, Director of Science Information, Division of Science and International Affairs Bureau, Ministry of Education, Science, Sports, and Culture, Tokyo, Japan Lela K. Riley, PhD, Associate Professor, Veterinary Pathobiology, University of Missouri, Columbia, MO William Shek, DVM, PhD, Director of Diagnostics, Charles River Laboratories, Wilmington, MA Toshiyuki Shibahara, DVM, PhD, Associate Professor, Laboratory Animal Center, Totori University, Yonago, Japan Abigail L. Smith, PhD, Department of Pathology, Medical Center, Loyola University, Maywood, IL John Strandberg, DVM, PhD, Director, Comparative Medicine, National Center for Research Resources, National Institutes of Health, Bethesda, MD Norikazu Tamaoki, MD, PhD, Professor Emeritus, Tokai University School of Medicine, Kanagawa, Japan William J. White, VMD, Senior Director, Professional Services, Charles River Laboratories, Wilmington, MA Judith L. Vaitukaitis, MD, Director of the National Center for Research Resources of the National Institutes of Health, Bethesda, MD John Vandenbergh, PhD, Professor, Department of Zoology, North Carolina State University, Raleigh, NC

Representative terms from entire chapter:

experimental animals